Key inflammatory mechanisms underlying heart failure
نویسندگان
چکیده
منابع مشابه
Key references on heart failure.
Molecular and Cellular Mechanisms Morgan HE, Baker KM. Cardiac hypertrophy: mechanical, neural, and endocrine dependence. Circulation. 1991;83:13-25. Review. Morgan HE. Cellular aspects of cardiac failure. Circulation. 1993;87(suppl IV):IV-4-IV-6. Review. Lakatta EG. Excitation-contraction coupling in heart failure. Hosp Pract. 1991;26:85-88, 91-98. Review. Morgan JP. Abnormal intracellular mod...
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Although neurohumoral antagonism has successfully reduced heart failure morbidity and mortality, the residual disability and death rate remains unacceptably high. Though abnormalities of myocardial metabolism are associated with heart failure, recent data suggest that heart failure may itself promote metabolic changes such as insulin resistance, in part through neurohumoral activation. A detrim...
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Despite being relatively recent, a growing and significant accumulation of experimental and clinical evidence has been observed that points to a gradual state of immune-inflammatory activation in patients with heart failure (HF). High levels of several cytokines are found in the circulation and cardiac muscle of individuals with HF, and invariably correlate with the severity of the disease. The...
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ژورنال
عنوان ژورنال: Herz
سال: 2019
ISSN: 0340-9937,1615-6692
DOI: 10.1007/s00059-019-4785-8